One other Examine Suggests Too A lot Fish Oil May Set off A-Fib | Well being Information

By Amy Norton HealthDay Reporter


WEDNESDAY, Oct. 13, 2021 (HealthDay Information) — A brand new examine confirms that fish oil dietary supplements might elevate the chance of a typical heart-rhythm dysfunction — significantly when doses high 1 gram per day.

At concern are medicines and dietary supplements containing omega-3 fatty acids, that are naturally present in fish oil.

Fish is taken into account a usually heart-healthy meals, however some research have linked omega-3 in capsule type to an elevated danger of atrial fibrillation, or a-fib.

In a-fib, the guts’s higher chambers quiver chaotically as a substitute of contracting successfully. It’s not instantly life-threatening, however over time it could result in issues akin to coronary heart failure or stroke.

However whereas some research have discovered a heightened danger of a-fib amongst omega-3 customers, others haven’t, mentioned Dr. Christine Albert, a professor of cardiology at Cedars-Sinai Medical Middle in Los Angeles.

So she and her colleagues carried out a meta-analysis, pulling collectively the outcomes of seven earlier medical trials testing omega-3 medicines and dietary supplements.

“With a meta-analysis, you’ll be able to see if there are results not detected in a single trial,” Albert mentioned.

The evaluation — printed just lately within the journal Circulation — concerned over 81,000 sufferers in whole. In the course of the examine interval, 3.6% developed a-fib.

Total, Albert and her staff discovered, trial members given omega-3 have been extra prone to develop a-fib over a mean of 5 years, versus these given a placebo.

And the dose mattered: Amongst sufferers taking greater than 1 gram per day, the chance of a-fib was 49% increased, in comparison with placebo customers. In distinction, the chance was elevated by solely 12% for sufferers taking 1 gram or much less per day.

Prescription-strength omega-3 fatty acids — manufacturers like Vascepa and Lovaza — are sometimes prescribed to folks with very excessive triglycerides, a kind of blood fats linked to elevated dangers of coronary heart assault and stroke.

Vascepa has additionally been proven to decrease the dangers of coronary heart assault and stroke when taken together with a cholesterol-lowering statin. That isn’t true, nevertheless, of different omega-3 medicines or over-the-counter dietary supplements.

Albert mentioned that individuals who’ve been prescribed omega-3 mustn’t cease taking it on their very own, however might need to speak with their physician concerning the danger of a-fib in the event that they have not already.

“I do not need to scare anybody,” Albert mentioned.

On the similar time, she added, folks ought to pay attention to the potential for creating a-fib whereas on omega-3 — and know the potential signs, akin to a speedy, fluttering heartbeat and dizziness.

Folks with attainable signs ought to inform their physician, Albert mentioned — although, she famous, a-fib can be symptom-free and will solely be detected throughout a medical appointment.

As for over-the-counter dietary supplements, Albert once more instructed folks converse to their physician. Despite the fact that they’re marketed as dietary supplements, she mentioned, it can’t be assumed they’re completely protected. Plus, proof of any coronary heart profit is missing.

“Consider it like taking a drug, and speak to your physician about whether or not it is best for you,” Albert mentioned.

For its half, the American Coronary heart Affiliation (AHA) encourages folks to get omega-3 from fish.

“Fish is a wonderful supply of omega-3 fatty acids, in addition to protein and plenty of different vital vitamins,” mentioned Linda Van Horn, a member of the AHA’s vitamin committee.

Particularly, folks ought to attempt for 2 weekly servings of fatty fish like salmon, trout or albacore tuna, mentioned Van Horn, who can be a professor of vitamin at Northwestern College Feinberg Faculty of Medication in Chicago.

“Fish oil dietary supplements usually are not the identical, and ought to be mentioned along with your well being care supplier,” she mentioned.

It is unclear why taking omega-3 may elevate a-fib danger, despite the fact that one prescription treatment seems to decrease coronary heart assault and stroke danger. However a-fib, which is an issue with the guts’s electrical exercise, differs from coronary heart assault and stroke — that are often attributable to blockages within the arteries.

And it’s believable, Albert mentioned, that omega-3 impacts the dangers of these situations otherwise.

SOURCES: Christine Albert, MD, MPH, professor, cardiology, and chair, Division of Cardiology, Smidt Coronary heart Institute, Cedars-Sinai Medical Middle, Los Angeles; Linda Van Horn, PhD, RD, professor and chief, vitamin division, Division of Preventive Medication, Northwestern College Feinberg Faculty of Medication, Chicago, and member, Vitamin Committee, American Coronary heart Affiliation, Dallas; Circulation, Oct. 6, 2021, on-line

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